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One Health

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One Health

Head of the Division: Dr. Panneer D, Scientist- C

Health is a continuum of being. Inter-sectional coordination is one of the cornerstones of Primary Health Care. Living in a shared eco-system; many of the diseases that affect us also affect animals and vice versa. The potential for new infections from various biomes is ever-present. Thus, a unified approach to address the range of health concerns from environmental to zoonotic takes on greater importance. The preservation and monitoring of the Human-Animal-Ecosystem Interface are essential to maintaining health and wellness in a global scenario.

'One Health' is an approach to designing and implementing programs, policies, legislation, and research in which multiple sectors communicate and work together to achieve better public health outcomes. (WHO) The relevant areas of work in healthcare include control of zoonotic diseases, food safety, and combatting antimicrobial resistance. The Unit of One Health at ICMR-VCRC, Puducherry is committed to research leadership with a targeted approach. We are a team of scholars, veterinarians, and doctors committed to exploring zoonotic diseases and multidisciplinary control measures. Equipped with a state-of-the-art laboratory, the UOH is leading the research on neglected tropical diseases that are vector-borne zoonoses affecting thousands of people annually

Objectives

1.To understand the interdependence of human health with animal health and ecosystems.

2.To investigate the epidemics of vector borne zoonotic diseases using an interdisciplinary and collaborative approach

3.To develop diagnostic tools for surveillance and diagnosis of vector-borne zoonotic diseases

4.To impart training and capacity building in One Health

Research Areas

Vector borne zoonotic diseases of public health importance, Acute undifferentiated febrile illness, Scrub Typhus- development of molecular and immunological diagnostics. Epidemiology of Tick-borne infections, neglected, emerging and re-emerging zoonoses.

Staff List
Sr. No.Name of the staffDesignation
1Dr. Panneer DScientist- C and Unit Head
2Dr.  Srikanth S.Scientist- B (Med.)
3Mrs. Waseema AScientist- B
4Mr. Anoop C ChoolayilScientist- B
5Dr. S. Lakshmi       Technician
6Mrs. S. PushpaTechnician
7Mr. S. RajkumarLaboratory Assistant-1
8Mr. SivakumarLaboratory Assistant-1
9Mr. P. SivapragasamLaboratory Assistant-1
10Mr. C. AravindasamyTechnician-III (Project)
11Mr. P. MariselvamTechnician-III (Project)
Ongoing Projects

Ongoing Projects

  • In-silico prediction and in-vitro evaluation of diagnostic epitopes of outer membrane protein B (ompB) of O. tsutsugamushi.

  • Development of a screening test for Orientia tsutsugamushi in rodents using recombinant 56KDa, ompA and Sca4 proteins.

  • Development of IgM ELISA and an antigen detection test for the diagnosis of scrub typhus in human/p>

  • Metagenomic profile of pathogens of public health importance in ticks and mites from Shimoga district, Karnataka.

  • Distribution of vector borne zoonotic diseases among undifferentiated acute febrile illness reported in a tertiary care centre

Completed Projects
Significant Research Findings/Contributions:
  • Significant Research Findings/Contributions:

    • A multiplex PCR protocol for the simultaneous detection of CHIKV, DENV and JEV in vectors has been developed.

    • 2. Natural infection of O. tsutsugamushi, the causative agent of scrub typhus was documented in animal reservoir host in Puducherry in areas with no reports of human cases of scrub typhus.

    • Multilocus Sequence Typing (MLST) protocol for the diagnosis of rickettsial pathogen by amplifying and sequencing the genes encoding ompA, ompB, Sca4, gltA and 16srRNA has been developed

    • Morphological identification of ticks and fleas using taxonomical keys was further confirmed by amplifying and sequencing the molecular markers such as 16srRNA, 18s rRNA and COX1 genes.

    • We first reported the presence of a rickettsial organism Rickettsia asembonensis in India, in Ctenocephalides felis felis (cat fleas) collected from the pet and domestic animals

Infra structure – Laboratories
  • Infra structure – Laboratories

    • Molecular Biology laboratory- Real time PCR/p>

    • Thermal cycler

    • Gradient PCR (Bio-Rad T100)

    • Gel documentation Unit

    • Electrophoresis units

    • Nano-pure water system

    • Analytical weighing balance

    • refrigerated micro centrifuge

    • Label printer

    • -40°C Freezer

    • Biosafety cabinet (BSL-IIB)

    • Spectrophotometer

    • Carbon dioxide incubator

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