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OMICS

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OMICS

Head of the Division: Dr. Vijesh Sreedhar Kuttiatt, Scientist-F

The "OMICS" disciplines aim at the universal detection of genes, mRNA, proteins and metabolites. Unit of OMICS is an initiative of ICMR-VCRC to undertake studies on genomics, proteomics and metabolomics relevant to vector-borne diseases.

Research Areas

VCRC has been conducting genomic studies of pathogens, vectors and hosts related to vector-borne diseases. With high throughput analysis of samples, omics technologies have revolutionised the field of modern biology and medicine. Utilising these advanced technologies, this unit would focus on studies which help in developing precise diagnostics and personalised medicines; identification of biomarkers and newer vector surveillance tools. The emerging discipline of proteogenomic and metabolomics in relation to vector borne diseases would be a priority area of research. The aim is to establish high-resolution accurate mass spectrometry-based assays, spectral libraries, data analysis platforms, and interfaces for proteomics and metabolomics of body fluids such as serum, saliva, sweat and urine of clinical cases presenting diagnostic and prognostic dilemma. In this direction we would be collaborating with various other institutions like medical colleges, research institutes, health departments throughout the country and also with research institutes abroad..

Staff List
Sr. No.Name of the staffDesignation
1Dr. Vijesh Sreedhar KuttiattHOD & Scientist-E
2Mrs. T. SankariSenior Technical officer
3Ms. V. ShakilaTechnician-1


Ongoing Projects

Ongoing Projects

  • Recurrent skin and soft tissue infections(SSTIs) in filarial lymphedema patients in Puducherry, south India etiological agents and the predisposing factor

  • Assessment of operational feasibility for piloting of wastewater surveillance for soil transmitted helminths

  • Immune response to the precautionary third dose of COVISHIELD/COVAXIN among the healthy adult population: an ICMR Cohort study, India

  • Prevalence of the natural Wolbachia infection in the wild population of Aedes aegypti mosquitoes from Tamil Nadu, South India

  • Verrucous and hyperkeratotic lesions in filarial lymphedema affected limbs: clinico - Pathological characteristics and association with HPV infection with HPV infection

  • Pilot study to screen for rickettsial pathogens in mosquitoes from rural areas of Puducherry.

  • Genetic lineage and drug resistance profile of malaria parasites prevailing in Kerala State


New Initiatives

  • Prevalence of the natural Wolbachia infection in the wild populations of A.aegypti mosquitoes from Tamilnadu, India
  • Genome wide scanning of Wuchereria bancrofti populations in India: elucidating molecular ecology and the genetic impact of Mass Drug Administration
Significant research findings/contributions
  • During 2017 dengue outbreak in Puducherry, our group had carried out serotyping and genotyping analysis on request of Health Department and had identified the circulation of dengue serotype-4 strain for the first time in Puducherry
Infrastructure (Labs)

The laboratory is equipped with Thermal cyclers, Horizontal Electrophoresis system, Gel documentation system, Real Time PCR, Laminar flow hood, Ultrapure water purification system, UV trans-illuminator, Refrigerated centrifuge, Biomedical freezers (-30° and -40°C) and Spectrophotometer) and Digital droplet PCR

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